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Research BloggingA collection of 8 posts

3 min read

Publication bias in clinical trials

Last week the New England Journal of Medicine (NEJM) published a paper on selective outcome reporting in clinical trials (Vedula et al. 2009). The primary and secondary outcome(s) of a clinical trial could for example...

2 min read

Mutation, selection and metastasis

Mutation and selection are important concepts in cancer biology. One well-known example is hereditary colon cancer. Patients with mutations in the DNA mismatch repair genes MLH1 or MSH2 develop colon cancer because of an increased rate...

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